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HealthNews RoundUp - 1st Week of September 2022
Update on The Moderna Vaccine Booster
Several days ago I reported that the Moderna Omicron Booster slated to be approved by the FDA and then the CDC for distributed was their bivalent mRNA 1273.214 vaccine. This vaccine contains mRNA that would encode for the original CoVid strain and the Omicron B.1 subvariant. This vaccine had been tested in a human clinical trail. It turns out that just before the FDA panel was considering their application, Moderna submitted another EUA application for a bivalent vaccine that contained mRNA to encode for spike proteins from the Omicron BA.4./BA.5 subvariants. This was the one that was approved.
So it turns out that both the Moderna and the Pfizer Omicron Boosters approved by the FDA and CDC both contain mRNAs that encode for both the original CoVid and the Omicron subvariants BA.4/BA.5. If it is time for your booster, which is the case for most of us, take your choice!
#moderna #omicron #booster #ba5 #pfizer
moderna, omicron, booster, ba5, pfizer
Details About Moderna’s New Omicron Booster-Now FDA-Approved
The CoVid Omicron booster that Moderna will release in the fall, called mRNA1273.214, is a bivalent shot containing mRNA that triggers production of antigen from the original CoVid and antigen from the B1.1.529 Omicron sub variant. This from data the company has submitted to the FDA for an EUA to cover use in those 12 years and older.
A 4th dose using this booster led to more than a 6 fold increase in Ba.4/BA.5 neutralizing antibodies in those without a CoVid infection history and more than a 3 fold rise in protective antibodies for those previously infected.
The local and and systemic reactions to the booster were slightly less severe and frequent than those to a 3rd dose of the original Moderna vaccine.
As I’m recording this broadcast today, August 31st, the FDA has just approved this booster. The CDC will be making a final decision tomorrow.
#moderna #CoVid #vaccine #booster #omicron #b5
moderna, CoVid, vaccine, booster, omicron, b5
Details About Pfizer’s New Omicron Booster-Now FDA Approved
Pfizer has developed two Omicron-targeting boosters: one is their Omicron BA.1 adapted vaccine and the other is their Omicron BA.4/BA.5 adapted vaccine. The former has been tested in humans while the latter has only been tested in mice and human studies are expected to begin soon.
Pfizer has applied to the FDA and the European Medicines Agency for EUAs for both versions. The BA.1 version contains mRNAs that encode for the antigens associated with both the original CoVid version and the Omicron BA.1 subvariant. The BA.4/BA.5 version contains the same mRNAs that encode for the antigens associated with both the original CoVid version but also mRNAs the encode for Omicron BA.4 and BA.5 subvariant antigens.
Pfizer has human data only for the BA.1 version and that shows a 9.1 fold rise in protective antibodies against BA.1. There is no human data regarding this booster’s protective antibodies against BA.4/BA.5. The mouse data shows shows a good protective antibody boost.
The FDA has today approved the BA.4/BA.5 adapted version without human test data. Scientists there have accepted Pfizer’s argument that this booster is fundamentally similar to their original vaccine and BA.1 booster in efficacy and safety. We’ll see tomorrow what the CDC decides before release to the general public.
#pfizer #CoVid #vaccine #booster #omicron #ba1 #ba5
pfizer, CoVid, vaccine, booster, omicron, ba1, ba5
Another CoVid Variant Waiting In The Wings
Omicron BA.5 is now beginning to wane, and we’re breathing a collective sigh of relief. Some bad news comes from Japan which is characterizing the next likely variant BA.2.75.
India was the site where BA.2.75 first popped up last spring and quickly eclipsed the BA.5 subvariant there. BA.2.75 is more transmissible than even BA.5 and has been detected in at least 34 countries globally and in at least 7 states in the US.
Japanese studies show that BA.2.75 binds to human cells more firmly, replicates faster, and seems to cause more lung damage than BA.5, our current subvariant. BA.5 seemes to preferentially infect the bronchial air passages.
It’s likely that BA.2.75 will be coming soon to your neighborhood. It slips by the current protective antibodies we acquired from vaccinations and infections better than BA.5. Some good news: it is responsive to the latest monoclonal antibody bebtelovimab.
#omicron #CoVid #ba275 #ba5 #bebtelovimab
omicron, CoVid, ba275, ba5, bebtelovimab
The Polypill Keeps Heart Attack Victims Healthy and Alive
When persons who survived a heart attack take a daily triple agent polypill, their risk of a second heart attack, stent placement or revascularization surgery, or stroke drops by 24% and their risk of death drops by 33%. Cardiac researchers from New York’s Mt. Sinai School of Medicine just reported these results in the New England Journal and presented them to the European Society of Cardiology after studying nearly 2500 patients ins 7 European countries.
This convenience polypill, marketed as Trinomia, contains low-dose aspirin to fight clotting and inflammation, ramipril to control blood pressure, and atorvastatin to normalize blood lipids. These drugs are often prescribed separately, but other studies reveal fewer than 50% of patients take them faithfully. That’s why the polypill, a convenience med, works so much better.
#polypill #trinomia #heartattsack #mi #stroke #revascularization
polypill, trinomia, heartattsack, mi, stroke, revascularization
Your CoVid Home Test Kit May Have Expired….Or Not
When home antigen tests for CoVid were first FDA approved, many of them had expiration dates in 4 to 6 months. As additional shelf life data has been accumulated, the FDA has extended those expirations dates in some cases to one year or as long as 18 months.
Problem is: the expiration date extension situation is different for each test kit brand and lot number. How do you find out if the test kits you have been squirreling away for months are still valid and accurate? Armed with your test kit brand and lot numbers, check the FDA site using this Bitly link: bit.ly/3PY7L6L. The site lists each brand and links to a sublist for info on specific lot numbers.
#CoVid #hometest #expiration #fda
CoVid #hometest #expiration #fda
Poliovirus Is Spreading
The reactivated poliovirus that first spread from Israel to upstate New York State’s Rockland and then Orange Counties, has now spread to the adjacent Sullivan County. No surprise, since the virus was already been detected downstate in the New York City’s wastewater systems.
Many people contract the poliovirus without becoming symptomatic, but, once infected, they can pass it on to others. One in every 200 infected persons will become paralyzed, often for life.
What you need to do is make certain that you are protected? If you live or will be traveling in the areas I mentioned or in any area where the poliovirus is circulating, say overseas, make certain that you are vaccinated and, if necessary boosted. If you never received the vaccine or aren’t certain, check with your medical team about beginning the 3 dose immunization series. If you were vaccinated years ago and were never boosted, get the one shot booster. This is particularly important if you are older, weakened by medical problems, or have known immunosuppression.
#polio #vaccination #booster #cdc #travel #immunosuppression
polio, vaccination, booster, cdc, travel, immunosuppression
Benefits of High Dose Flu Vaccine
High dose flu vaccine reduces the risk of hospitalization by 64% and the risk of death by 49% for older persons. From the University of Copenhagen comes this study of 12,477 participants. Half received the high dose vaccine containing 4 times the dose of each flu antigen. The other half served as controls and received the standard dose vaccine.
Preventing the flu is critical, particularly for older persons. Studies have shown a 6 fold increased risk of heart attack during the week following a positive influenza test.
The time for flu vaccination will soon be upon us. In the US, the high dose flu vaccine is recommended for all those 65 yrs and older as well as for those at higher risk due to medical problems. Ask for high dose when you book your vaccine appointment.
#influenza #highdosevaccine #heartattack
influenza #highdosevaccine #heartattack
Monkeypox Presentation and Complications
To better understand this rapidly spreading disease, French infectious disease researchers reviewed the records of 264 PCR-confirmed monkeypox patients. 99% were men with a median age of 35 years, 29% were HIV-positive, 71% were taking PrEP, and 11% were smallpox-vaccinated.
In 53%, there were no symptoms such as fever or lymph node swelling prior to the appearance of skin lesions. Complications occurred in 36%. All but one patient developed a bacterial superinfection requiring antibacterials. Hospitalization was required in 6% for cellulitis, severe gastrointestinal infection, and other miscellaneous issues. No mention was made in the study of TPOXX use.
#monkeypox #complications #hospitalization
monkeypox, complications, hospitalization
E-Cigarette Aerosols Promote CoVid Infection
The inhaled vapors from electronic cigarettes significantly increase the numbers of the ACE2 CoVid-binding sites and the TMPRSS2 protease that helps the virus infect human cells. UC-Riverside molecular biologists report these worrisome findings following their assessment of the effects from genuine JUUL aerosols as well of the individual aerosol components nicotine, propylene glycol, and vegetable glycerin.
Bottom line: puffing on e-cigarettes will make you more susceptible to a severe CoVid infection.
#CoVid #ace2 #tmprss2 #ecigarette #juul #nicotine
CoVid, ace2, tmprss2, ecigarette, juul, nicotine
Viruses Can Fight Cancer
We all view most viruses as “bad guys” as we go through our 3rd year trying to avoid and survive CoVid. Some viruses known as oncolytic viruses are “good guys” that can turbocharge the immune system to more effectively kill cancer cells that spread and threaten to kill us. Immunologists at North Carolina’s Wake Forest School of Medicine and the University of Arizona have harnessed these viruses to do just that.
The technique uses the rabbit poxvirus myxoma that can selectively infect human cancer cells while leaving normal cells unharmed. The virus weakens and kills some of the tumor cells directly, but it also puts a target on their heads.
The second part of the treatment involves taking a patient’s own T lymphocytes and sensitizing them to myxoma antigens before reinjecting them. Once back in the body, these modified T cells hone to the viral-infected cancer cells and break them open by immune-mediated autolysis.
This exciting oncolytic viral therapy is now experimental but should be coming soon to the clinic.
#oncolyticvirus #myxoma #immunotherapy #car #tcr
oncolyticvirus, myxoma, immunotherapy, car, tcr
Universal Flu Vaccine
The biomedical researchers at Georgia State University have designed a universal flu vaccine containing less variable proteins from both Influenza A and B virus including the multi-neuraminidase proteins and the universally present M2 ectodomain protein. This vaccine has, to date, only been tested on mice but it was found to protect them from infection by a slew of diverse influenza viruses that include the influenza A seasonal variants H1N1, H5N1, H3N2, H9N2 and H7N9 as well as the Yamagata and Victoria lineage influenza B viruses. The next step: testing in ferrets that possess respiratory tracts similar to humans. Then, no doubt, on to the clinic.
#influenza #universalvaccine #influenzaA #influenzaB
influenza, universalvaccine, influenzaA, influenzaB
Smart Socks Help Prevent Falls
Somewhat wobbly persons who shouldn’t leave their beds, stand up, and try to walk unassisted, often do leading to the all too predictable falls, broken wrists, and fractured hips. Ohio State University nurse researchers report the successful use of PUP Smart Socks that wirelessly alert clinicians that a sock wearer is getting up and putting pressure on their feet. In a study of 569 fall-prone patients, use of these sock sensors reduced patient falls by 80%. The socks are manufactured by the Ohio company Palarum.
#smartsock #falls #alarm #fractures #palarum
smartsock, falls, alarm, fractures, palarum
Nanorobots Might Someday Brush Your Teeth
In the future, your electric toothbrushes and waterflossers may be obsolete. Precision dentistry researchers at the University of Pennsylvania have developed a nano robotic system using iron oxide nanoparticles that can be assembled into bristles and motorized by computer-controlled magnetic fields to roll over your teeth and gums and remove all debris. Even better, the iron oxide activates hydrogen peroxide that degrades biofilms and kills bacteria before it can trigger gum infections. Work is now ongoing on a consumer-level prototype that can be commercialized.
#nanorobots #dentistry #toothbrushing #flossing #ironoxide #gingivitis
nanorobots, dentistry, toothbrushing, flossing, ironoxide, gingivitis
Google Will Help Women Seeking Reproductive Choice
This tech giant has announced that its Google Maps will now label healthcare facilities that are verified as offering reproductive services to women as “provides abortions” and those so-called “crisis pregnancy centers” that do not as “might not provide abortions.” A Bloomberg News study showed that online searches by women seeking abortion services often lead them to facilities that not only do not provide pregnancy terminations but also try to dissuade them from doing so. To preserve privacy, Google is also automatically deleting the searcher’s location data when a user launches sensitive searches such as those for abortion services.
#google #abortion #pregnancy #pregnancycrisiscenter #privacy
google, abortion, pregnancy, pregnancycrisiscenter, privacy
Medicare Advantage Is Growing
Over the past 15 years, Medicare Advantage membership has increased 2.5 fold. Now, 48% of Medicare is delivered through the HMO-like Advantage programs vs. traditional fee-for-service Medicare. The shift from Classic to Advantage Medicare has been escalating in the past 2 years with 8-10% of subscribers shifting per year.
The vast majority of members receive their care through just 2 Advantage programs. United HealthCare has 28% of Advantage enrollees while Humana services 18%. After these two, Blue Cross/Blue Shield has 14%, CVS Health 11%, Kaiser 6%, and 23% are spread among other insurers. All but 1% of these plans require the hated prior authorizations for most except preventive services.
#medicare #advantage #hmo #unitedhealthcare #humana #priorauth
medicare, advantage, hmo, unitedhealthcare, humana, priorauth
New Motorcycle Helmet Protects Against More Than Head Injuries
The latest helmet from India’s Shellios Technolabs filters the air that the wearer breathes via a HEPA filter and battery operated air handling system located at the back of the helmet so as to not obstruct the rider’s vision. It provides clean, pollution-free air just behind the helmet’s clear visor and it rids of air of 80% of otherwise inhaled toxins. The helmet weighs 3.3 pounds and costs $56.
#motorcycle #helmet #hepa #pollution #filtration
motorcycle, helmet, hepa, pollution, filtration
Long CoVid Attacking The Workforce
Persistent CoVid symptoms are keeping over 4 million Americans from their jobs. This according to a Brookings Institution study that finds nearly 16 million persons 18 to 65 years of age have Long CoVid and lose from $170-230 billion in lost wages each year. This disease takes a big bite out of Americans’ discretionary income as well as US economic performance.
#longcovid #CoVid #jobs #income #gdp
longcovid, CoVid, jobs, income, gdp
Otter MOMO Children’s Sandals Have Lead
The CPSC and Kolan are recalling Otter MOMO Children’s Sandals. The inner layer of these sandals contains lead levels higher than that allowable by federal safety standards. Lead is a neurotoxin and a danger to the developing brains of children. About 100 pairs of these sandals were sold online at amazon.com. Immediately stop your children from wearing these scandals. Contact Kolan at 1-888-928-5118 or via email at email@example.com to receive safe disposal instructions for the product and a refund.
#Otter #scandals #lead #poisoning #children #recall
Otter, scandals, lead, poisoning, children, recall
Yuboloo Infant Bath Seats Can Drown Your Baby
The CPSC and Yuboloo have recalled Yuboloo Infant Bath Seats. This product fails to meet federal safety standards for infant bath seats as it is unstable, has unsafe leg openings, and is prone to tipping over creating a drowning hazard for babies. About 1,050 of these bath seats were sold online at amazon.com. Do not bathe your infant in these bath seats. Contact Yubaloo via the email firstname.lastname@example.org to receive a prepaid mailer for return of the product and to register for a refund.
#yubaloo #infantbathseat #unstable #drowning #infants #recall
yubaloo, infantbathseat, unstable, drowning, infants, recall
UPPAbaby All-Terrain RIDGE Jogging Strollers Could Amputate a Child’s Fingers
The CPSC and UPPAbaby have recalled all UPPAbaby All-Terrain RIDGE Jogging Strollers. The rear disc brakes on this stroller have openings that can amputate a non-occupant child’s fingers should they get caught while the stroller is moving. About 14,400 strollers were sold at BuyBuyBaby, Nordstrom, Neiman Marcus, Pottery Barn Kids and other children’s stores and specialty stores nationwide and online at Amazon.com. Immediately discontinue use of these strollers and contact UPPAbaby by phone at 1-844-823-3132 for via email at email@example.com to receive free replacement brake discs for both wheels.
#uppababy #stroller #brakes #amputation #children #recall
uppababy #stroller #brakes #amputation #children #recall
Novogratz Brand Outdoor Metal Hanging Chairs May Tip and Fall
The CPSC and HomeGoods are recalling Novogratz brand Outdoor Metal Hanging Chairs. This chair may tip over or the chair’s suspension chain may break leading to the occupant falling and sustain injuries. About 5,000 chairs were sold in the US and about 194 chairs were sold in Canada at xHomeGoods and Homesense stores and HomeGoods/T.J. Maxx or Marshalls combination stores nationwide. Immediately discontinue use of these chairs and return them to any HomeGoods, Homesense or HomeGoods/T.J. Maxx or Marshalls combination stores to receive either a full refund or store credit. For more information, phone HomeGoods at 1-800-888-0776 or Homesense at 1-855-660-4663.
#novogratz #hangingchair #fall #injury #recall
novogratz, hangingchair, fall, injury, recall
Sun Joe Cordless Lawn Mowers Have Loose Blades
The CPSC and the Snow Joe company are recalling Sun Joe Cordless Lawn Mowers models 24V-X2-17LM and 24V-X2-17LM-CT. These mowers have loose blades that may fly off and create laceration hazards for the operator or bystanders. About 26,300 of these mowers were sold in the US and about 350 were sold in Canada. Do not use these mowers until you have contacted Snow Joe at 1-800-641-2917 or via email at firstname.lastname@example.org to determine if your mower is included in the recall. If so, you will receive instructions for securing the mower blade.
#sunjoe #mower #blade #lacerations #recall
sunjoe, mower, blade, lacerations, recall
Three Golden Coins Dried Mushrooms Have Bacterial Contamination
The FDA and Tai Phat Wholesalers, LLC are recalling Three Golden Coins Dried Whole or Sliced Mushrooms. These mushrooms are contaminated with salmonella. This bacterium causes a severe gastroenteritis that may progress into a life-threatening systemic infection in the very young, older frail individuals, and those with weakened immune systems. This produce was sold in specialty retail stores in: Florida, Georgia, Kentucky, Maryland, Massachusetts, Minnesota, Mississippi, New Hampshire, New Jersey, New York, North Carolina, Pennsylvania, South Carolina, Tennessee, and Virginia. If you bought these mushrooms, don’t consume them. Return them to the place of purchase for a full refund. If you need more information, contact Tai Phat Wholesalers at 1-703-538-8000.
#threecoins #mushrooms #salmonella #infection #recall
threecoins, mushrooms, salmonella, infection, recall
Keswick Creamery Cheeses Are Contaminated with Listeria
The FDA and the Keswick Creamery are recalling the following cheese varieties: Calverley Cheese, Vulkwin’s Folly Cheese, Vermeer Cheese, Havarti Cheese, Wallaby Cheese, Cider Washed Tomme Cheese, Feta Cheese, Whole Milk Ricotta, Bovre Cheese (plain, oregano and garlic, herbes de provence, cranberry and honey) and Quark Cheese (plain, dill and onion). These cheeses are contaminated with listeria monocytogenes. This bacterium causes a severe and sometimes fatal systemic infection in the very young, older frail individuals, and those with weakened immune systems. Listeria can also trigger miscarriages and stillbirths. All of this affected cheese was sold at Dupont Circle Freshfarm Market in Washington, D.C.; Takoma Park Farmers Market in Takoma Park, Maryland; Smith Meadows Farm Store in Berryville, Virginia; Oylers Organic Farms and Market in Biglerville, Pennsylvania; and Talking Breads Farm Store in Mechanicsburg, Pennsylvania. If you bought this cheese, don’t consume it and discard the product. For more information and to arrange a refund, contact Keswick Creamery by phone at 1-800-946-1631 or via email at email@example.com.
#keswick #cheese #listeria #infection #recall
keswick, cheese, listeria, infection, recall
Whole Foods Market 365 Organic Creamy Caesar Dressing Has Allergens
The FDA and Van Law Food Products Inc.now recall Whole Foods Market 365 Organic Creamy Caesar Dressing. This product contains undeclared soy and wheat allergens. Those with an allergy to soy or wheat or who have gluten sensitivity or celiac disease could develop a serious or life-threatening allergic reaction should they consume this product. The affected product has a Best By Date of 04/06/2023. This caesar dressing was sold in the produce or dairy department of Whole Foods in the states of Alabama, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Michigan, Minnesota, Mississippi, Missouri, Nebraska, New Jersey, New Mexico, New York, North Carolina, Ohio, South Carolina, Tennessee, Texas, Utah, Wisconsin, and Wyoming. If you bought this caesar dressing, don't consume it and return it to the place of purchase for a full refund. For more information, contact Van Law Foods by phone at 1-844-936-8255.
#wholefoods #caesardressing #soy #wheat #gluten #celiac #allergy #recall
wholefoods, caesardressing, soy, wheat, gluten, celiac, allergy, recall
Piantedosi Rolls and Buns Have Bacterial Contamination
The FDA and the Piantedosi Baking Company, Inc. are recalling select dinner rolls, sandwich rolls and bun products. These baked goods have a glaze that come from the Lyons Magnus company and is contaminated with Cronobacter sakazakii and/or Clostridium botulinum. These bacteria can cause severe or life-threatening infections and a a particular danger in the very young, older frail individuals, and those with weakened immune systems. If you bought any of those baked goods, don't consume them and dispose of them. For more information and to arrange a refund, contact the Piantedosi Baking Company by phone at 1-800-339-0080 x165.
#piantedosi #rolls #buns #bacteria #infection #recall
piantedosi, rolls, buns, bacteria, infection, recall
Market Pantry White Fudge Animal Cookies May Contain Metal Fragments
The FDA and the D. F. Stauffer Biscuit Co. are recalling Market Pantry White Fudge Animal Cookies. These cookies may contain metal fragments that could trigger dental injuries and lacerations to the mouth, throat, and other portions of the gastrointestinal tract. The affected product has a Best By Date of 21FEB2023 and a Lot #Y052722. If you bought these cookies, don't consume them and return them to the place of purchase for a full refund. If you need more information, contact the D.F. Stauffer Biscuit Co. at 1-888-480-1988.
#MarketPantry #animalcookies #foreignbodies #lacerations #recall
MarketPantry, animalcookies, foreignbodies, lacerations, recall
St. James Smokehouse Scottish Salmon Has Listeria Contamination
The FDA and St. James Smokehouse have recalled 93 cases of St. James Smokehouse brand, Scotch Reserve Scottish Smoked Salmon, 4oz Packages lot# 123172. These fish are contaminated with listeria monocytogenes. This bacterium causes a severe and sometimes fatal systemic infection in the very young, older frail individuals, and those with weakened immune systems. Listeria can also trigger miscarriages and stillbirths. These fish were sold at various retailers in Alabama, Colorado, Florida, Illinois, New Jersey, New York, Massachusetts, Washington State, Virginia, and Wisconsin as well as at Safeway stores in Washington State. Don't consume this product and return it to the place of purchase for a full refund. For more information, contact St. James Smokehouse by phone at 1-305-461-0231.
#stjamesmokehouse #salmon #listeria #infection #recall
stjamesmokehouse, salmon, listeria, infection, recall
GreenWise Animal Crackers Have Treenuts
The FDA and Toufayan Bakery are recalling GreenWise Animal Crackers. These crackers contain undeclared tree nuts. Those with an allergy to tree nut could develop a serious or life-threatening allergic reaction should they consume this product. The affected product has an expiration date of Feb 05, 2023. These animal crackers were sold by Publix Supermarkets in Florida, Alabama, Georgia, South Carolina, North Carolina, Virginia and Tennessee. If you bought these animal crackers, don't consume them and return the package to the place of purchase for a full refund. For more information, call the Toufayan Bakery at 1-813-754-5565.
#greenwise #animalcrackers #publix #treenuts #allergy #recall
greenwise, animalcrackers, publix, treenuts, allergy, recall
ReadyMeals Brand Cooked Shrimp with Cocktail Sauce and Snow Crab Legs Imitation Surimi Contain Undeclared Allergens
The FDA and Albertsons are expanding their recall of ReadyMeals seafood items to Cooked Shrimp with Cocktail Sauce and Snow Crab Legs Imitation Surimi. These products contain unspecified allergens not listed on the ingredient labels. These products were sold at Safeway and Albertsons located in Oregon and in select cities in Washington state. If you bought these shrimp and crab legs, don't consume them and return the product to the place of purchase for a full refund. For additional information, contact Albertsons Customer Service Center at 1-877-723-3929.
#albertsons #safeway #shrimp #crablegs #allergens #recall
albertsons, safeway, shrimp, crablegs, allergens, recall